Article

Human hypothalamic neural stem cells transplantation ameliorates age-associated dysfunction through SNS/eNAMPT axis activation in aged mice

2024-05-24

Abstract excerpt

The hypothalamus is the brain region that regulates systemic body metabolism and multiple brain functions. The adult hypothalamus harbors neural stem/precursor cell (NSC)-like cells. Along with age-related body changes, the hypothalamic NSC (htNSC) population declines, indicating the potential of htNSC replacement as an anti-aging strategy. Here, we developed protocol to generate htNSCs from human pluripotent stem...

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Literature Corpus work: 84c7dfd3-3226-56de-8d93-ce87f6059f3c
DOI: 10.1101/2024.05.23.595504

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