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GPI-anchorless prion disease is sensitive to oxidative stress and shows potential for treatment with edaravone, based on iPS-derived neuron study

2025-04-03

Abstract excerpt

<title>Abstract</title> <p>Only a few reports have generated induced pluripotent stem cells from patients with prion diseases, making it important to conduct translational studies using cells derived from individuals with prion protein (<italic>PRNP</italic>) mutations. In this study, we established induced pluripotent stem cells from a patient with a glycosylphosphatidylinositol-anchorless <italic>PRNP</italic>...

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Literature Corpus work
a802ca53-6ab3-5a6e-8e57-03570f5b82ab
DOI
10.21203/rs.3.rs-6001571/v1
Open publication

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