Article

Elevating Jak-STAT signaling via SOCS3 deletion sustains photoreceptor viability and visual function in mouse models of retinitis pigmentosa

2025-07-11

Abstract excerpt

<title>Abstract</title> Retinitis pigmentosa (RP) is an inherited retinal disease in which the loss of rod photoreceptors precedes cone photoreceptor degeneration. The neurocytokine ciliary neurotrophic factor (CNTF) can provide potent neuroprotection for photoreceptors in various retinal degeneration models and has thus been tested in clinical trials aimed at treating blinding diseases. In a preclinical model...

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Literature Corpus work: a7fceb8d-d0f1-5feb-adca-fe10ca9f9c87
DOI: 10.21203/rs.3.rs-7089882/v1

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