Article

Retinitis Pigmentosa Results in Neurodegeneration Concomitant With Neuroinflammation, Extracellular Matrix Disorganization and the Upregulation of Neuroprotective Pathways in Glial Cells and Neurons

2020-11-10

Abstract excerpt

<title>Abstract</title> <p>BackgroundHereditary retinal degenerations like retinitis pigmentosa (RP) are amongst the leading causes of blindness in younger patients. To enable <italic>in vivo</italic> investigation of cellular and molecular mechanisms responsible for photoreceptor cell death and to allow testing of therapeutic strategies that could prevent retinal degeneration, animal models have been created. He...

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Literature Corpus work: b95e9547-aba1-5aef-868f-181827497530
DOI: 10.21203/rs.3.rs-101559/v1

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