Article

Retinal ganglion cell survival after severe optic nerve injury is modulated by crosstalk between JAK/STAT signaling and innate immune responses in the zebrafish retina

2021-04-10

Abstract excerpt

<h4>ABSTRACT</h4> Visual information is transmitted from the eye to the brain along the optic nerve, a structure composed of retinal ganglion cell (RGC) axons. The optic nerve is highly vulnerable to damage in neurodegenerative diseases like glaucoma and there are currently no FDA-approved drugs or therapies to protect RGCs from death. Zebrafish possess remarkable neuroprotective and regenerative abilities and he...

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Literature Corpus work: 1350c833-d38c-5bef-8963-d0c34a6f9bb4
DOI: 10.1101/2021.04.08.439090

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