Article

HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice

2019-12-13

Abstract excerpt

Cone photoreceptor cell death in inherited retinal diseases, such as Retinitis Pigmentosa (RP), leads to the loss of high acuity and color vision and ultimately to blindness. In RP, a vast number of mutations perturb the structure and function of rod photoreceptors while cones remain initially unaffected. Cone death follows rod death secondarily due to increased oxidative stress, inflammation, and loss of structur...

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Literature Corpus work: 077c0045-64bf-5cb7-9c63-9c00601587d9
DOI: 10.1101/2019.12.13.874339

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