Article

Inhibition of <i>agr</i> Quorum Sensing in Staphylococci by Novel Thiazole-Indole Hybrid Compounds

2025-10-16

Abstract excerpt

The rise of multidrug-resistant Staphylococcus aureus has prompted the search for innovative, non-bactericidal therapeutic strategies. Anti-virulence approaches targeting quorum sensing (QS) pathways offer a promising alternative by disarming pathogenicity, potentially without exerting selective pressure for resistance. In this study, we report the identification of two novel thiazole–indole hybrid compounds, nam...

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Literature Corpus work: a7eeb367-a9c3-5a06-80d3-640eda32f150
DOI: 10.1101/2025.10.15.682726

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