Article

Drug-like Fragments Inhibit <i>agr-</i> Mediated Virulence Expression in <i>Staphylococcus</i> aureus

2019-02-01

Abstract excerpt

In response to the increasingly problematic emergence of antibiotic resistance, novel strategies for combating pathogenic bacteria are being investigated. Targeting the agr quorum sensing system, which regulates expression of virulence in Staphylococcus aureus , is one potentially useful approach for combating drug-resistant pathogens that has not yet been fully explored. A previously published study of a fragme...

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Literature Corpus work: a0710427-fc63-5308-8327-dd87fe2cad04
DOI: 10.1101/538173

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