Article

Co-expression-based models improve eQTL predictions and highlight novel transcriptome-wide genes associated with schizophrenia

2026-02-11

Abstract excerpt

Non-coding genetic variants statistically associated with complex heritability phenotypes are thought to act primarily through transcriptome regulatory mechanisms. Predictions of gene expression in tissue like the human brain traditionally rely primarily on cis -eQTLs. Here, we introduce INGENE and MODULE, trans -eQTLs models designed to enhance the prediction of gene expression by capturing the collective impac...

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Literature Corpus work: a7e7f431-8b5d-5de8-9751-100456f9df2c
DOI: 10.64898/2026.02.10.704353

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