Article

Investigating trait variability of gene co-expression network architecture in brain by manipulating genomic signatures of schizophrenia risk

2021-05-07

Abstract excerpt

<h4>ABSTRACT</h4> While the role of genomic risk for schizophrenia on brain gene co-expression networks has been described, the patterns of its manifestations are varied and complex. To acquire a deeper understanding of this issue, we implemented a novel approach to network construction by manipulating the RNA-Seq expression input to “integrate” or “remove” the “modulatory” effects of genomic risk for schizophren...

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Literature Corpus work: 860e41ed-a4b7-5dce-97c5-527b3f9803ad
DOI: 10.1101/2021.05.04.442668

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