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Article

Illuminating links between cis-regulators and trans-acting variants in the human prefrontal cortex.

Genome medicine - 24 Nov 2022

Liu Shuang, Won Hyejung, Clarke Declan, Matoba Nana, Khullar Saniya, Mu Yudi, Wang Daifeng, Gerstein Mark

Abstract excerpt

BACKGROUND: Neuropsychiatric disorders afflict a large portion of the global population and constitute a significant source of disability worldwide. Although Genome-wide Association Studies (GWAS) have identified many disorder-associated variants, the underlying regulatory mechanisms linking them to disorders remain elusive, especially those involving distant genomic elements. Expression quantitative trait loci...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36424644
DOI: 10.1186/s13073-022-01133-8
PMCID: PMC9685876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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