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Concordance and deviations of the PDX tumors from the primary tumors of NSCLC patients: effects of murine fibroblasts on low engraftment rates

2023-06-06

Abstract excerpt

Patient-derived xenograft(PDX) models of primary lung cancer have been reported. However, varying engraftment rates and their underlying mechanisms for specific subtypes of lung cancer (adenocarcinoma, squamous cell carcinoma, and large cell neuroendocrine carcinoma) have not been studied. The authors prepared subcutaneous tumors grown in NSG™ mice with primary tumors of lung cancer patients to develop lung cancer...

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Literature Corpus work
a7b923f1-1d6a-54ea-aa26-0a33083a9494
DOI
10.21203/rs.3.rs-2930778/v1
Open publication

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Concordance and deviations of the PDX tumors from the primary tumors of NSCLC patients: effects of murine fibroblasts on low engraftment ratesDOI 10.21203/rs.3.rs-2930778/v1
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