Article

Activation of Notch1 drives the development of radiation-induced thymic lymphoma in p53 wild-type mice

2020-08-21

Abstract excerpt

<h4>ABSTRACT</h4> Mouse models of radiation-induced thymic lymphoma are widely used to study the development of radiation-induced blood cancers and to gain insights into the biology of human T-lymphoblastic leukemia/lymphoma. Here, we aimed to determine key oncogenic drivers for the development of radiation-induced thymic lymphoma by performing whole-exome sequencing using tumors and paired normal tissues from mi...

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Literature Corpus work: a766c670-53b0-54ee-b36c-a07b93f8c83c
DOI: 10.1101/2020.08.21.261487

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