Article

Pinpointing the decisive role of TP53 mutations in orchestrating immunosuppression in head and neck squamous cell carcinoma

2024-01-02

Abstract excerpt

<h4>Background: </h4> The head and neck squamous cell carcinoma (HNSCC) is the sixth common cancer worldwide and can be affected by multiple etiological factors. The immuno-combination therapies recently demonstrated superior performance but efficient biomarkers for outcome prediction is still lacking. Genetically, TP53 gene demonstrated highest alternation frequency in HNSCC. The lucid elaboration on the intercon...

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Literature Corpus work: a716f111-23d9-572b-a03a-50886c235f9d
DOI: 10.21203/rs.3.rs-3789512/v1

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