Article

Multimodal genomic markers predict immunotherapy response in the head and neck squamous cell carcinoma

2021-03-30

Abstract excerpt

<h4>ABSTRACT</h4> Immune checkpoint blockade (ICB) therapy has had a major impact on the clinical management of head and neck squamous cell carcinoma (HNSCC). However, clinical responses to ICB are observed in only a fraction of patients. In the present paper, we used multimodal approaches to a) evaluate the utility of existing ICB biomarkers including tumor mutation burden (TMB), microsatellite instability (MSI)...

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Literature Corpus work: 50eec2f6-a41a-518f-8a42-6446228fe874
DOI: 10.1101/2021.03.30.437691

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