Article

Predicting therapeutic responses in head and neck squamous cell carcinoma from TP53 mutation and The mutation of TP53 could be detected by cfDNA

2023-03-08

Abstract excerpt

<h4>Objectives: </h4> Head and neck squamous cell carcinoma (HNSCC) was increasing globally. The mutation of the TP53 was the most common of all somatic genomic changes in HNSCC, and TP53 mutation was associated with the response of immunotherapeutic and chemotherapeutic. Tumor-derived circulating cell-free DNA (cfDNA) was minimally invasive method to determine genetic alterations for cancer. The study aimed to ex...

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Literature Corpus work: 0f746c04-6e09-5ac3-acd1-8ed1910b0317
DOI: 10.21203/rs.3.rs-2552100/v1

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