Article
Tumor Mutation Burden, Immune Cell Infiltration, and Construction of Immune-Related Genes Prognostic Model in Head and Neck Cancer.
International journal of medical sciences - 1 Jan 2021
Jiang Ai-Min, Ren Meng-Di, Liu Na, Gao Huan, Wang Jing-Jing, Zheng Xiao-Qiang, Fu Xiao, Liang Xuan, Ruan Zhi-Ping, Tian Tao, Yao Yu
Abstract excerpt
Background: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, and the prognosis of HNSCC remains bleak. Numerous studies revealed that the tumor mutation burden (TMB) could predict the survival outcomes of a variety of tumors. Objectives: This study aimed to investigate the TMB and immune cell infiltration in these patients and construct an immune-related genes (IRGs)...
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