Article

TP53 mutation-associated immunosignatures impact on anti-PD-L1 treatment response in head and neck cancer patients.

2023-03-01

Abstract excerpt

<h4>Background: </h4> Immune checkpoint inhibitors (ICIs) are a therapeutic strategy for various cancers although only a subset of patients respond to the therapy. Identifying patients more prone to respond to ICIs may increase the therapeutic benefit and allow studying new approaches for resistant patients. <h4>Methods: </h4>. We analyzed the TCGA cohort of HNSCC patients in relation to their activation of 26 im...

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Literature Corpus work: e6340162-2dbd-53da-8f69-d5963bad8816
DOI: 10.21203/rs.3.rs-2620802/v1

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