Article

Hemoxygenase-1 as a key mediator of acute radiation pneumonitis revealed in a human lung alveolus-on-a-chip

2023-02-13

Abstract excerpt

<h4>ABSTRACT</h4> Exposure to gamma radiation either due to environmental disasters or cancer radiotherapy can result in development of acute radiation syndrome (ARS), characterized by pneumonitis and lung fibrosis. We leveraged a microfluidic organ-on-a-chip lined by human lung alveolar epithelium interfaced with pulmonary endothelium to model acute radiation-induced lung injury in vitro . Both lung epithelium...

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Literature Corpus work: 070b1b1d-4f96-59fd-9c60-5ae81c92ff13
DOI: 10.1101/2023.02.13.528339

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Hemoxygenase-1 as a key mediator of acute radiation pneumonitis revealed in a human lung alveolus-on-a-chipDOI 10.1101/2023.02.13.528339Read

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