Article

Recapitulating SARS-CoV-2 Infection in a Human Lung Organoid-on-a-Chip at the Air-Liquid Interface

2026-08-20

Abstract excerpt

<title>Abstract</title> <p>Background Chronic respiratory diseases and emerging pathogens such as SARS-CoV-2 are a major global health burden. Traditional in vitro models, however, poorly recapitulate the functional complexity of the human lung, limiting mechanistic study and therapeutic development. Methods To address this, we developed a lung organoid-on-a-chip in which patient-derived airway organoids are di...

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Literature Corpus work: 205feb15-7f78-5950-b7e1-6b0b4c941db1
DOI: 10.21203/rs.3.rs-10547160/v1

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