Article

Modeling Fire-Related Smoke Inhalation Injury Using the Human Lung-on-a-Chip and Organoid Platform: Pathogenesis Insights and Therapeutic Evaluation

2024-11-07

Abstract excerpt

Fire-related smoke inhalation-induced acute lung injury (SI-ALI) is a prevalent condition in modern fires, characterized by high mortality and a lack of targeted therapeutic options. Previous research has been hindered by instability in smoke generation and modeling methods, limiting the investigation of SI-ALI mechanisms. This study, for the first time, utilized organ-on-a-chip and organoid technologies, optimizi...

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Literature Corpus work: 5ae32c59-7e10-540f-b9e2-959b34b2275f
DOI: 10.22541/au.173099195.56580136/v1

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