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Article

A vascularized human lung-on-a-chip reveals compartmentalized inflammatory responses in bacterial pneumonia

2024-09-20

Abstract excerpt

<title>Abstract</title> <p>The lung serves as a primary organ for gas exchange in the human body. However, during clinically apparent lung insults such as bacterial pneumonia, the blood-alveolar barrier is disrupted, immune cells are recruited, and lung biomechanics are altered. These processes impair lung function acutely with major contributions from the lung vasculature. The pulmonary vasculature normally prov...

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Literature Corpus work
ef047ae9-c04b-59fe-8f0d-25e6561ee32f
DOI
10.21203/rs.3.rs-3343362/v1
Open publication

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A vascularized human lung-on-a-chip reveals compartmentalized inflammatory responses in bacterial pneumoniaDOI 10.21203/rs.3.rs-3343362/v1
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