Article

Plasma amyloid β levels are driven by genetic variants near <i>APOE, BACE1, APP, PSEN2:</i> A genome-wide association study in over 12,000 non-demented participants

2017-09-27

Abstract excerpt

<h4>INTRODUCTION</h4> There is increasing interest in plasma Aβ as an endophenotype and biomarker of Alzheimer’s disease (AD). Identifying the genetic determinants of plasma Aβ levels may elucidate important processes that determine plasma Aβ measures. <h4>METHODS</h4> We included 12,369 non-demented participants derived from eight population-based studies. Imputed genetic data and plasma Aβ1-40, Aβ1-42 levels a...

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Literature Corpus work: a6ce6924-36d4-5807-b66d-5f5b89cd069c
DOI: 10.1101/194266

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