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Alzheimer's Disease Investigated via Gene-Environment Interactions, Biochemical Pathways, Cellular Processes, and Disease Phenotype Variability

2024-05-14

Abstract excerpt

<title>Abstract</title> <p>Background: Alzheimer's disease (AD) is a neurodegenerative disorder influenced by genetic and environmental factors. APOE, APP, PSEN1, PSEN2, CLU, SORL1, BIN1, CR1, PICALM, TREM2, ABCA7, and CD33 play key roles in AD pathogenesis, affecting biochemical pathways and cellular processes. However, the interaction between genetic predisposition and environmental factors, as well as the rea...

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Literature Corpus work: 036dd159-2dcf-5d4a-be8f-a01d1100495d
DOI: 10.21203/rs.3.rs-4408464/v1

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