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Article

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.

Molecular psychiatry - 1 Jan 2021

Yan Qi, Nho Kwangsik, Del-Aguila Jorge L, Wang Xingbin, Risacher Shannon L, Fan Kang-Hsien, Snitz Beth E, Aizenstein Howard J, Mathis Chester A, Lopez Oscar L, Demirci F Yesim, Feingold Eleanor, Klunk William E, Saykin Andrew J, Cruchaga Carlos, Kamboh M Ilyas

Abstract excerpt

Deposition of amyloid plaques in the brain is one of the two main pathological hallmarks of Alzheimer's disease (AD). Amyloid positron emission tomography (PET) is a neuroimaging tool that selectively detects in vivo amyloid deposition in the brain and is a reliable endophenotype for AD that complements cerebrospinal fluid biomarkers with regional information. We measured in vivo amyloid deposition in the brains...

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Identifiers

PMID: 30361487
DOI: 10.1038/s41380-018-0246-7
PMCID: PMC6219464

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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