Article
Classical DC2 subsets and monocyte-derived DC: Delineating the developmental and functional relationship.
European journal of immunology - 1 Mar 2023
Backer Ronald A, Probst Hans Christian, Clausen Björn E
Abstract excerpt
To specifically tailor immune responses to a given pathogenic threat, dendritic cells (DC) are highly heterogeneous and comprise many specialized subtypes, including conventional DC (cDC) and monocyte-derived DC (MoDC), each with distinct developmental and functional characteristics. However, the functional relationship between cDC and MoDC is not fully understood, as the overlapping phenotypes of certain type 2...
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