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Article

Human dendritic cell subsets: an update.

Immunology - 1 May 2018

Collin Matthew, Bigley Venetia

Abstract excerpt

Dendritic cells (DC) are a class of bone-marrow-derived cells arising from lympho-myeloid haematopoiesis that form an essential interface between the innate sensing of pathogens and the activation of adaptive immunity. This task requires a wide range of mechanisms and responses, which are divided between three major DC subsets: plasmacytoid DC (pDC), myeloid/conventional DC1 (cDC1) and myeloid/conventional DC2...

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Identifiers

PMID: 29313948
DOI: 10.1111/imm.12888
PMCID: PMC5904714

Genes

BATF3
IKZF1
KLF4
ZEB2

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