Article
Engineered <i>Bacillus subtilis</i> as oral probiotics to enhance clearance of blood lactate
2023-12-01
Abstract excerpt
Elevated lactate concentrations are implicated in various acute and chronic diseases such as sepsis and mitochondrial dysfunction, respectively. Conversely, ineffective lactate clearance is associated with poor clinical prognoses and high mortality in these diseases. While several groups have proposed using small molecule inhibitors and enzyme replacement to reduce circulating lactate, there are few practical and...
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Identifiers and source
- Literature Corpus work
- a6b271b4-cc0f-575b-b892-1791ad156a2c
- DOI
- 10.1101/2023.11.30.569300