Article

Biocontainment strategies for <i>in vivo</i> applications of <i>Saccharomyces boulardii</i>

2022-12-27

Abstract excerpt

The human gastrointestinal tract is a complex and dynamic environment, playing a crucial role in human health. Microorganisms engineered to express a therapeutic activity have emerged as a novel modality to manage numerous diseases. Such advanced microbiome therapeutics (AMTs) must be contained within the treated individual. Hence safe and robust biocontainment strategies are required to prevent the proliferation...

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Literature Corpus work: ad7d647c-9410-523b-9fc0-96ff142b7af8
DOI: 10.1101/2022.12.27.522029

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