Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosures

Abstract excerpt

<h4>ABSTRACT</h4> Dynamic transitions between cell states underlie both normal physiology and disease. However, most single-cell technologies capture only static snapshots. To address this gap, we developed a platform that integrates light-guided hydrogel polymerization with computer vision to generate on-demand compartments around live cells, enabling longitudinal imaging of cellular behavior paired with whole-t...

Topics

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• Adipose Tissue
• Lipopolysaccharides
• NF-KappaB Inhibitor alpha
• Organ Specificity
• RNA-Seq
• Sequence Analysis, RNA
• Single-Cell Analysis
• Stromal Cells

Identifiers and source

Literature Corpus work

f2276039-6d74-50bd-ad2c-bb6cac6100c1

DOI

10.64898/2026.05.05.723030