Article

Exome Sequencing of Glioblastoma-Derived Cancer Stem Cells Reveals Rare Clinically Relevant Frameshift Deletion in MLLT1 Gene

2021-08-24

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Glioblastoma multiforme (GBM) is a heterogeneous CNS neoplasm which causes significant morbidity and mortality. One reason for the poor prognostic outcome of GBM is attributed to the presence of cancer stem cells (CSC) which confer resistance against standard chemo- and radiotherapeutics modalities. Two types of GBM-associated CSC were isolated from the same pat...

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Literature Corpus work: a645db02-7340-5db8-b39b-564750f9a5c8
DOI: 10.21203/rs.3.rs-754227/v1

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