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Article

Patient-derived glioblastoma cell lines with conserved genome profiles of the original tissue.

Scientific data - 12 Jul 2023

Kim Soon-Chan, Cho Young-Eun, Shin Young-Kyoung, Yu Hyeon Jong, Chowdhury Tamrin, Kim Sojin, Yi Kyung Sik, Choi Chi-Hoon, Cha Sang-Hoon, Park Chul-Kee, Ku Ja-Lok

Abstract excerpt

Glioblastoma (GBM) is the most lethal intracranial tumor. Sequencing technologies have supported personalized therapy for precise diagnosis and optimal treatment of GBM by revealing clinically actionable molecular characteristics. Although accumulating sequence data from brain tumors and matched normal tissues have facilitated a comprehensive understanding of genomic features of GBM, these in silico evaluations...

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Identifiers

PMID: 37438387
DOI: 10.1038/s41597-023-02365-y
PMCID: PMC10338444

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