Article

Epigenomic and functional dynamics of human bone marrow myeloid differentiation to mature blood neutrophils

2018-04-05

Abstract excerpt

<h4>Summary</h4> Neutrophils are short-lived blood cells that play a critical role in host defense against infections. To better comprehend neutrophil functions and their regulation, we provide a complete epigenetic and functional overview of their differentiation stages from bone marrow-residing progenitors to mature circulating cells. Integration of epigenetic and transcriptome dynamics reveals an enforced regu...

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Literature Corpus work: a64123b1-f7bb-56aa-9d0d-21d10465a69c
DOI: 10.1101/295014

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