Article

NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs

2019-05-03

Abstract excerpt

Maintenance and expression of mitochondrial DNA is indispensable for proper function of the oxidative phosphorylation machinery. Post-transcriptional modification of mitochondrial RNA has emerged as one of the key regulatory steps of human mitochondrial gene expression. Mammalian NOP2/Sun RNA Methyltransferase Family Member 2 (NSUN2) has been characterised as an RNA methyltransferase that introduces 5-methylcytosi...

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Literature Corpus work: a5e081f8-0239-5c21-8f79-eda4097326fa
DOI: 10.1101/626960

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