Article

Decoding molecular programs in melanoma brain metastases

2022-02-08

Abstract excerpt

The systemic dissemination of tumor cells and the spatiotemporal development of organ- metastases are associated with loss of therapeutic control and decreased overall survival (OS). The emergence of solitary or multiple brain metastases is frequently observed in melanoma patients and responsible for disease progression and dismal prognosis. Here, we used whole transcriptome and methylome profiling as well as targ...

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Literature Corpus work: a537d27a-bcb6-5d83-981e-c82e3837d203
DOI: 10.1101/2022.02.06.22270509

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