Article

MET receptor activation by stromal cells serves as promising target in melanoma brain metastases

2023-10-16

Abstract excerpt

The development of brain metastases hallmarks disease progression in 20-40% of melanoma patients and is a serious obstacle to therapy. Understanding the processes involved in the development and maintenance of melanoma brain metastases (MBM) is critical for the discovery of novel therapeutic strategies. Here, we generated transcriptome and methylome profiles of MBM showing high or low abundance of infiltrated Iba1...

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Literature Corpus work: 75aa8987-7285-577d-ac43-429dde35aae4
DOI: 10.1101/2023.10.16.23297080

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