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Article

Epigenomic landscape of melanoma progression to brain metastasis: unexplored therapeutic alternatives.

Epigenomics - 1 Jan 2015

Marzese Diego M, Witz Isaac P, Kelly Daniel F, Hoon Dave S B

Abstract excerpt

Melanoma brain metastasis is a complication with rising incidence. Despite the high rate of somatic mutations driving the initial stages of melanocyte transformation, the brain colonization requires a phenotypic reprogramming that is, in part, influenced by epigenomic modifications. This special report summarizes recent findings in the epigenomic landscape of melanoma progression to brain metastasis, with...

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Identifiers

PMID: 26638944
DOI: 10.2217/epi.15.77

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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