Article

Topological defects govern mesenchymal condensations, offering a morphology-based tool to predict cartilage differentiation

2022-05-30

Abstract excerpt

A critical initial stage of skeletal morphogenesis involves formation of highly compact aggregates of mesenchymal cells, known as mesenchymal condensations, appearing as regularly-spaced pattern of spots. Conventional computational models to understand their patterning have been based on chemotaxis, haptotaxis, and reaction-diffusion equations. In this work, we investigate the mesenchymal condensations from a diff...

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Literature Corpus work: a5004657-2666-5e3d-91c4-bb860fe64eb7
DOI: 10.1101/2022.05.30.493944

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