Article

The Caenorhabditis elegans Shugoshin regulates TAC-1 in cilia

2022-12-23

Abstract excerpt

The conserved Shugoshin (SGO) protein family has essential roles in mediating proper chromosome segregation from yeast to humans. SGO proteins have been implicated in diverse roles in and out of the nucleus; SGO activity inhibits incorrect spindle attachment in the kinetochore, regulates the spindle assembly checkpoint (SAC), and ensures centriole cohesion in the centrosome. These functions involve different micro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a4dfdd9d-2fc5-545b-9be4-30773374f095
DOI: 10.21203/rs.3.rs-2327706/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Caenorhabditis elegans Shugoshin regulates TAC-1 in ciliaDOI 10.21203/rs.3.rs-2327706/v1Read

<i>C. elegans</i> SAS-1 ensures centriole integrity and ciliary function, and operates with SSNA-1Semantic proximity Read

Shugoshin promotes efficient activation of spindle assembly checkpoint and timely spindle disassemblySemantic proximity Read

Human Shugoshin mediates kinetochore-driven formation of kinetochore microtubules.Semantic proximity Read

An SMC-like protein binds and regulates Caenorhabditis elegans condensins.Semantic proximity Read

Identification of novel synaptonemal complex components in C. elegans.Semantic proximity Read

Suppressors of zyg-1 define regulators of centrosome duplication and nuclear association in Caenorhabditis elegans.Semantic proximity Read

Shugoshin 2 regulates localization of the chromosomal passenger proteins in fission yeast mitosis.Semantic proximity Read

The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus.Semantic proximity Read

The <i>C. elegans</i> homolog of Sjögren’s Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assemblySemantic proximity Read

Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity.Semantic proximity Read

Structure and function of the PP2A-shugoshin interaction.Semantic proximity Read

D-box is required for the degradation of human Shugoshin and chromosome alignment.Semantic proximity Read