Article
Identification of novel synaptonemal complex components in C. elegans.
The Journal of cell biology - 4 May 2020
Hurlock Matthew E, Čavka Ivana, Kursel Lisa E, Haversat Jocelyn, Wooten Matthew, Nizami Zehra, Turniansky Rashi, Hoess Philipp, Ries Jonas, Gall Joseph G, Rog Ofer, Köhler Simone, Kim Yumi
Abstract excerpt
The synaptonemal complex (SC) is a tripartite protein scaffold that forms between homologous chromosomes during meiosis. Although the SC is essential for stable homologue pairing and crossover recombination in diverse eukaryotes, it is unknown how individual components assemble into the highly conserved SC structure. Here we report the biochemical identification of two new SC components, SYP-5 and SYP-6, in...
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