Article

<i>C. elegans</i> SAS-1 ensures centriole integrity and ciliary function, and operates with SSNA-1

2025-04-24

Abstract excerpt

Centrioles are microtubule-based organelles critical for signaling, motility and division. The microtubule-binding protein SAS-1 is homologous to the human ciliopathy component C2CD3 and contributes to centriole integrity in C. elegans , but how this function is exerted is incompletely understood. Here, through the generation of a null allele and analysis with U-Ex-STED, we establish that SAS-1 is dispensable for...

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Literature Corpus work: 59269b16-16ad-52e8-bdbb-cbc80b067772
DOI: 10.1101/2025.04.22.650004

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