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Article

The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleus.

Cell - 26 Dec 2003

Malone Christian J, Misner Lisa, Le Bot Nathalie, Tsai Miao-Chih, Campbell Jay M, Ahringer Julie, White John G

Abstract excerpt

The centrosome and nucleus are intimately associated in most animal cells, yet the significance of this interaction is unknown. Mutations in the zyg-12 gene of Caenorhabditis elegans perturb the attachment of the centrosome to the nucleus, giving rise to aberrant spindles and ultimately, DNA segr...

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PMID: 14697201
DOI: 10.1016/s0092-8674(03)00985-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14697201-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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