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Repurposing pitavastatin and atorvastatin to overcome chemoresistance of metastatic colorectal cancer under high glucose conditions

2024-04-09

Abstract excerpt

<title>Abstract</title> <p>Background Colorectal cancer (CRC) poses a significant clinical challenge because of drug resistance, which can adversely impact patient outcomes. Recent research has shown that abnormalities within the tumor microenvironment, especially hyperglycemia, play a crucial role in promoting metastasis and chemoresistance, and thereby determine the overall prognosis of patients with advanced...

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Literature Corpus work
a4532e20-7253-58d4-bd08-419e29b588dc
DOI
10.21203/rs.3.rs-4218809/v1
Open publication

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Repurposing pitavastatin and atorvastatin to overcome chemoresistance of metastatic colorectal cancer under high glucose conditionsDOI 10.21203/rs.3.rs-4218809/v1
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