Multi-omics integration identifies a selective vulnerability of colorectal cancer subtypes to YM155.

Abstract excerpt

Tumor heterogeneity is a major challenge to the treatment of colorectal cancer (CRC). Recently, a transcriptome-based classification was developed, segregating CRC into four consensus molecular subtypes (CMS) with distinct biological and clinical characteristics. Here, we applied the CMS classification on CRC cell lines to identify novel subtype-specific drug vulnerabilities. We combined publicly available...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Caco-2 Cells
• Share to Cell Survival