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Article

Synergistic therapeutic effects of metformin at a clinically relevant dosage in combination with chemotherapy via the AKT/mTOR pathway on ovarian cancer

2020-08-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Ovarian cancer is the leading cause of cancer-related death among women. Complete cytoreductive surgery followed by platinum-taxene chemotherapy has been the gold standard for a long time. Various compounds have been assessed in an attempt to combine them with conventional chemotherapy to improve survival rates or even overcome chemoresistance. Many studies have s...

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Literature Corpus work
94ecd3a0-5f27-537e-8924-7f193ee6e15d
DOI
10.21203/rs.2.14622/v2
Open publication

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Synergistic therapeutic effects of metformin at a clinically relevant dosage in combination with chemotherapy via the AKT/mTOR pathway on ovarian cancerDOI 10.21203/rs.2.14622/v2
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