Article

Early-stage colon cancer with high MALAT1 expression is associated with the 5-Fluorouracil resistance and future metastasis

2022-03-29

Abstract excerpt

<h4>Background: </h4> This study aimed to investigate the role of long noncoding RNA (LncRNA) expression profiles to predict relapse and 5-FU response in patients with stage I/II colon cancer (CC). <h4>Methods and Results: </h4> The expression level of 15 LncRNA was analyzed in stage I/II colon tumors of 126 CC patients. To confirm the findings in-vitro, 5FU-resistant HT29 cells were generated by subjecting HT-29...

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Literature Corpus work: 694f4d3d-1874-5c69-b76c-606032f2b4bd
DOI: 10.21203/rs.3.rs-1401692/v1

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