Article

Bioinformatic Analysis of Transcriptome Changes Underlying Metformin-induced Reversal of Drug Resistance in Head and Neck Squamous Cell Carcinoma Cells

2021-09-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Metformin is the first-line drug for type II diabetes, and recent studies indicate that metformin plays an inhibitory role in multiple cancers. Metformin can also enhance the effect of chemotherapy. Although head and neck squamous cell carcinoma cells are sensitive to metformin, the mechanisms related to the metformin response and the chemosensitization effect h...

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Literature Corpus work: 6d26d7fc-6c40-5638-ae94-16280b66685b
DOI: 10.21203/rs.3.rs-880051/v1

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