Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Novel miRNAs, Targeting Genes, Signaling Pathway, and the Small Molecule for Overcoming Oxaliplatin Resistance of Metastatic Colorectal Cancer

1 Jan 2022

Abstract excerpt

One of the globally common cancers is colorectal cancer (CRC). At present, a surgical approach remains a good option for CRC patients; however, 20% of surgically treated CRC patients experience metastasis. Currently, even the first‐line used drug, oxaliplatin, remains inadequate for treating metastatic CRC, and its side effect of neurotoxicity is a major problem when treating CRC. The Gene Omnibus GSE42387...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cancer Mechanisms and Therapy
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36193307
DOI: 10.1155/2022/3825760

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Novel miRNAs, Targeting Genes, Signaling Pathway, and the Small Molecule for Overcoming Oxaliplatin Resistance of Metastatic Colorectal CancerPMID 36193307Read ↗

In silico analysis to identify miR-1271-5p/PLCB4 (phospholipase C Beta 4) axis mediated oxaliplatin resistance in metastatic colorectal cancerSemantic proximity Read ↗

TGM2, HMGA2, FXYD3, and LGALS4 genes as biomarkers in acquired oxaliplatin resistance of human colorectal cancer: A systems biology approachSemantic proximity Read ↗

Identification of a six-gene signature predicting overall survival for Oxaliplatin and 5-Fluorouracil resistant Colon cancer and potential drug-repurposingSemantic proximity Read ↗

Delineating the underlying molecular mechanisms and key genes involved in metastasis of colorectal cancer via bioinformatics analysis.Semantic proximity Read ↗

GABRP is a potential chemoresistance regulator in colorectal cancerSemantic proximity Read ↗

Identifying the key genes and microRNAs in colorectal cancer liver metastasis by bioinformatics analysis and in�vitro experimentsSemantic proximity Read ↗

Identification of novel biomarkers affecting the metastasis of colorectal cancer through bioinformatics analysis and validation through qRT-PCRSemantic proximity Read ↗

A mitophagy-related gene signature associated with prognosis and immune microenvironment in colorectal cancerSemantic proximity Read ↗

miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cellsSemantic proximity Read ↗

Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancerSemantic proximity Read ↗

Identification of a Six-Gene Signature Predicting Overall Survival for Oxaliplatin and 5-Fluorouracil Resistant Colon Cancer and Potential Drug-RepurposingSemantic proximity Read ↗

Bioinformatic analysis for the identification of potential gene targeting drug resistance in CRCSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.