Article
Role of the B-cell receptor in chronic lymphocytic leukemia: where do we stand?
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia - 1 Jan 2010
Fais Franco, Bruno Silvia, Ghiotto Fabio
Abstract excerpt
The past 15 years have witnessed an enormous effort in studying B-cell Chronic Lymphocytic Leukemia. A great number of researches brought significant novel information and a better understanding of the natural history of this disease. This mini review will focus on the studies related to the Immunoglobulin variable (IgV) genes rearrangements that compose the B-cell receptor (BcR) of the leukemic clones. These...
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