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Article

MicroRNAs and B cell receptor signaling in chronic lymphocytic leukemia

19 Apr 2013

Abstract excerpt

The relative expression levels of certain microRNAs (miRNAs) correlate with known prognostic markers in chronic lymphocytic leukemia (CLL), such as leukemia-cell expression of zeta-associated protein of 70 kDa (ZAP-70), use of unmutated immunoglobulin heavy-chain variable region genes (IGHV), chromosomal abnormalities or dysfunctional p53. Here we review studies that provide evidence suggesting that certain...

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PMID: 23597135
DOI: 10.3109/10428194.2013.796055

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